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Northern Inuit Bundle DNA test at Canine Genetic Testing

Northern Inuit Bundle

Original price was: £114.00.Current price is: £99.18. Incl. VAT

Find out if your Northern Inuit could develop an inherited disease at CAGT.

Select at least two tests from the selection below to build a bundle of your choice at discounted rates.

Oculoskeletal Dysplasia

Degenerative Myelopathy

Important information about the relevance of this variant in most breeds.

CODE NIT_BUNDLE
Category
Turnaround 1-4 weeks
Breed(s)
Aliases

Overview

A number of tests are available for the Northern Inuit. Two or more of these tests purchased as part of this bundle will be discounted.

  1. Oculoskeletal dysplasia associated with the COL9A3 gene
  2. Degenerative Myelopathy associated with the SOD1 gene

Oculoskeletal dysplasia (OSD)

Oculoskeletal dysplasia (OSD) is an inherited disease characterised by skeletal and ocular defects. Skeletal defects include disproportionate shortlimbed dwarfism (short appendages with a normal trunk/body) and skeletal dysplasia (retarded or deformative bone growth. Ocular defects consist of combinations of corneal opacities, enlarged globes, cataract formation, vitreous, optic nerve and retinal abnormalities. The skeletal and ocular abnormalities are visible from a very young age (< 3 months). The ocular defects progress in severity, resulting in loss of vision and eventually blindness.

Degenerative Myelopathy

Important: Degenerative Myelopathy is a rare disease that presents most commonly in German Shepherd Dogs and Boxers, sporadically in Pembroke Welsh Corgis, Cardigan Welsh Corgis, Bernese Mountain Dogs, Rhodesian Ridgebacks, Borzoi and Chesapeake Bay Retrievers. It is rarely diagnosed in other breeds or mixed-breed dogs. DM is considered genetically complex and will have more than one contributing genetic variant. The variant targeted by this test is widespread and found in more than 120 breeds. However, association of the variant with the disease has only been shown in very few breeds and should never be used to inform breeding decisions, except where close relatives have been clinically diagnosed.

Canine degenerative myelopathy (previously also known as chronic degenerative radiculomyelopathy) is a progressive disease of the spinal cord in older dogs. Most dogs are at least 8 years old before clinical become apparent. DM usually starts with a muscle weakness, loss of muscle and loss of coordination (ataxia) in the hind limbs. Progression is generally quote slow, but dogs will eventually be crippled within approximately 3 years of the onset of disease.

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